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Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells

Jérémy Dufloo , Cyril Planchais , Stéphane Frémont , Valerie Lorin , Florence Guivel-Benhassine , et al.
Nature Communications, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Article dans une revue pasteur-03654220v1
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Deep learning enabled label-free microfluidic droplet classification for single cell functional assays

Thibault Vanhoucke , Angga Perima , Lorenzo Zolfanelli , Pierre Bruhns , Matteo Broketa
Frontiers in Bioengineering and Biotechnology, 2024, 12, pp.1468738. ⟨10.3389/fbioe.2024.1468738⟩
Article dans une revue pasteur-04703977v1
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Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

Delphine Planas , Isabelle Staropoli , Vincent Michel , Frederic Lemoine , Flora Donati , et al.
Nature Communications, 2024, 15 (1), pp.2254. ⟨10.1038/s41467-024-46490-7⟩
Article dans une revue pasteur-04530809v1
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TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice

Véronique Godot , Colas Tcherakian , Laurine Gil , Iñaki Cervera-Marzal , Guangming Li , et al.
PLoS Pathogens, 2020, 16, ⟨10.1371/journal.ppat.1009025⟩
Article dans une revue hal-04296375v1

Lack of ADCC breadth of human non-neutralizing anti-HIV-1 antibodies.

Timothée Bruel , Florence Guivel-Benhassine , Valérie Lorin , Hugues Lortat-Jacob , Françoise Baleux , et al.
Journal of Virology, 2017, 91 (8), pp.e02440-16. ⟨10.1128/JVI.02440-16⟩
Article dans une revue hal-01487928v1
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Qualitative monitoring of SARS-CoV-2 mRNA vaccination in humans using droplet microfluidics

Matteo Broketa , Aurélien Sokal , Michael Mor , Pablo Canales-Herrerias , Angga Perima , et al.
JCI Insight, 2023, In press. ⟨10.1172/jci.insight.166602⟩
Article dans une revue pasteur-04111772v1
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Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers

Stéphane Marot , Isabelle Malet , Valentin Leducq , Karen Zafilaza , Delphine Sterlin , et al.
Nature Communications, 2021, 12 (1), pp.844. ⟨10.1038/s41467-021-21111-9⟩
Article dans une revue hal-03138467v1
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Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

Jonathan Torres , Gabriel Ozorowski , Emanuele Andreano , Hejun Liu , Jeffrey Copps , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (20), pp.e2120976119. ⟨10.1073/pnas.2120976119⟩
Article dans une revue pasteur-04082754v1
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Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies

Timothée Bruel , Karl Stéfic , Yann Nguyen , Donatella Toniutti , Isabelle Staropoli , et al.
Cell Reports Medicine, 2022, 3 (12), pp.100850. ⟨10.1016/j.xcrm.2022.100850⟩
Article dans une revue pasteur-04165260v1
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High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1

William Bolland , Vincent Michel , Delphine Planas , Mathieu Hubert , Isabelle Staropoli , et al.
Journal of Virology, 2024, 98 (1), pp.e0135123. ⟨10.1128/jvi.01351-23⟩
Article dans une revue pasteur-04369613v1
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A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations

Ludivine Grzelak , Sarah Temmam , Cyril Planchais , Caroline Demeret , Laura Tondeur , et al.
Science Translational Medicine, 2020, 12 (559), pp.eabc3103. ⟨10.1126/scitranslmed.abc3103⟩
Article dans une revue pasteur-03139185v1
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Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies

Jérémy Dufloo , Ludivine Grzelak , Isabelle Staropoli , Yoann Madec , Laura Tondeur , et al.
Cell Reports Medicine, 2021, 2 (5), pp.100275. ⟨10.1016/j.xcrm.2021.100275⟩
Article dans une revue pasteur-03229805v1
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IgA dominates the early neutralizing antibody response to SARS-CoV-2

Delphine Sterlin , Alexis Mathian , Makoto Miyara , Audrey Mohr , François Anna , et al.
Science Translational Medicine, 2020, pp.eabd2223. ⟨10.1126/scitranslmed.abd2223⟩
Article dans une revue hal-03105620v1
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Escape of SARS-CoV-2 Variants KP.1.1, LB.1, and KP.3.3 From Approved Monoclonal Antibodies

Delphine Planas , Isabelle Staropoli , Cyril Planchais , Emilie Yab , Banujaa Jeyarajah , et al.
Pathogens and Immunity, 2024, 10 (1), pp.1-11. ⟨10.20411/pai.v10i1.752⟩
Article dans une revue pasteur-04748459v1
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Dual neutralization of influenza virus hemagglutinin and neuraminidase by a bispecific antibody leads to improved antiviral activity

Romila Moirangthem , Sapir Cordela , Dina Khateeb , Ben Shor , Ivan Kosik , et al.
Molecular Therapy, In press, 32 (10), ⟨10.1016/j.ymthe.2024.07.023⟩
Article dans une revue pasteur-04669709v1

SARS-CoV-2 Omicron BA.1 breakthrough infection drives late remodeling of the memory B cell repertoire in vaccinated individuals

Aurélien Sokal , Giovanna Barba-Spaeth , Lise Hunault , Ignacio Fernandez , Matteo Broketa , et al.
Immunity, 2023, 56 (9), pp.2137-2151.e7. ⟨10.1016/j.immuni.2023.07.007⟩
Article dans une revue hal-04309010v1
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Variants with the N501Y mutation extend SARS-CoV-2 host range to mice, with contact transmission

Xavier Montagutelli , Matthieu Prot , Laurine Levillayer , Eduard Baquero Salazar , Grégory Jouvion , et al.
2023
Pré-publication, Document de travail pasteur-04168583v1
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Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models

Alice Dejoux , Qianqian Zhu , Christelle Ganneau , Odile Richard-Le Goff , Ophélie Godon , et al.
Science Translational Medicine, 2024, 16 (764), pp.eado4463. ⟨10.1126/scitranslmed.ado4463⟩
Article dans une revue pasteur-04706288v1

Flow Cytometry Analysis of HIV-1 Env Conformations at the Surface of Infected Cells and Virions: Role of Nef, CD4, and SERINC5

Isabelle Staropoli , Jérémy Dufloo , Anaïs Ducher , Pierre-Henri Commère , Anna Sartori-Rupp , et al.
Journal of Virology, 2020, 94 (6), ⟨10.1128/JVI.01783-19⟩
Article dans une revue pasteur-02561978v1

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

Delphine Planas , Nell Saunders , Piet Maes , Florence Guivel-Benhassine , Cyril Planchais , et al.
Nature, 2022, 602 (7898), pp.671-675. ⟨10.1038/s41586-021-04389-z⟩
Article dans une revue pasteur-03654259v1
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Sex Differences in the Evolution of Neutralizing Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2

Ludivine Grzelak , Auréie Velay-Rusch , Yoann Madec , Floriane Gallais , Isabelle Staropoli , et al.
Journal of Infectious Diseases, 2021, 224 (6), pp.983-988. ⟨10.1093/infdis/jiab127⟩
Article dans une revue hal-03606632v1
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Anti‐ HIV ‐1 antibodies trigger non‐lytic complement deposition on infected cells

Jérémy Dufloo , Florence Guivel-Benhassine , Julian Buchrieser , Valérie Lorin , Ludivine Grzelak , et al.
EMBO Reports, 2019, 21 (2), pp.e49351. ⟨10.15252/embr.201949351⟩
Article dans une revue pasteur-03239697v1
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Omicron BA.1 breakthrough infection drives long-term remodeling of the memory B cell repertoire in vaccinated individuals

Aurélien Sokal , Giovanna Barba-Spaeth , Lise Hunault , Ignacio Fernández , Matteo Broketa , et al.
2023
Pré-publication, Document de travail pasteur-03986461v1

SARS‐CoV‐2 Alpha, Beta, and Delta variants display enhanced Spike‐mediated syncytia formation

Maaran Michael Rajah , Mathieu Hubert , Elodie Bishop , Nell Saunders , Remy Robinot , et al.
EMBO Journal, 2021, 40 (24), pp.e108944. ⟨10.15252/embj.2021108944⟩
Article dans une revue pasteur-03654276v1

Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies

Delphine Planas , Timothée Bruel , Ludivine Grzelak , Florence Guivel-Benhassine , Isabelle Staropoli , et al.
Nature Medicine, 2021, ⟨10.1038/s41591-021-01318-5⟩
Article dans une revue pasteur-03207907v1

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

Delphine Planas , David Veyer , Artem Baidaliuk , Isabelle Staropoli , Florence Guivel-Benhassine , et al.
Nature, 2021, 596 (7871), pp.276-280. ⟨10.1038/s41586-021-03777-9⟩
Article dans une revue pasteur-03696844v1

Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies

Olivier Schwartz , Thierry Prazuck , Benjamin Terrier , Emmanuel André , Etienne Simon-Loriere , et al.
Nature Medicine, 2022, ⟨10.1038/s41591-022-01792-5⟩
Article dans une revue pasteur-03654237v1
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Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2

Nell Saunders , Delphine Planas , William Bolland , Christophe Rodriguez , Slim Fourati , et al.
EBioMedicine, 2022, 77, pp.103934. ⟨10.1016/j.ebiom.2022.103934⟩
Article dans une revue pasteur-03654246v1
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HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria

Cyril Planchais , Luis M Molinos-Albert , Pierre Rosenbaum , Thierry Hieu , Alexia Kanyavuz , et al.
Nature Communications, 2023, 14 (1), pp.6326. ⟨10.1038/s41467-023-42027-6⟩
Article dans une revue hal-04248132v1
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Analysis of mRNA vaccination-elicited RBD-specific memory B cells reveals strong but incomplete immune escape of the SARS-CoV-2 Omicron variant

Aurélien Sokal , Matteo Broketa , Giovanna Barba-Spaeth , Annalisa Meola , Ignacio Fernández , et al.
Immunity, 2022, 55 (6), pp.1096-1104.e4. ⟨10.1016/j.immuni.2022.04.002⟩
Article dans une revue hal-03652602v1