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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
138
Publications avec texte intégral
Open Access
53 %
Mots clés
Acetylcholinesterase deficiency
Glucocorticoid-receptor
Cell penetrating peptide
Gene editing
Myotonic dystrophy
CRISPRi
Cardiac muscle
MBNL
Diaphragm
Mouse model
Therapy
ARN
Muscle
Alternative splicing
CMS
Autophagy
Exercice
ACETYLCHOLINESTERASE
Thérapie génique
Dystrophie Myotonique
Astrocyte
Myotonic dystrophy type 1
Gene Therapy
BIOLOGIE MOLECULAIRE
PacBio
Neuron
Glutamate
Myotonic Dystrophy Type 1
Intermediate filament
KNOCKOUT MICE
Animals
Mouse models
Fibrosis
Humans
Glucocorticoids
Mice
Glial cells
Maximal force
Myelin
Brain
Brain dysfunction
Knockout
DM1
Quantitative microdialysis
Astrocytes
Trinucleotide Repeat Expansion
Cell model
Hypoxia
Dynamin 2
Duchenne muscular dystrophy
Transgenic mouse
Myotonic Dystrophy
In vivo
Exercise
Motoneuron
Aging
Skeletal muscle
Dystrophin
RNA splicing
Dilated cardiomyopathy
RNA biology
Oligodendrocytes
Dystrophie myotonique
CTG repeat contractions
Gene therapy
Trinucleotide repeat expansion
Long read sequencing
Cell culture model
Desmin
Muscular dystrophy
Acute coronary syndrome
AAV
Genotype phenotype correlation
Transgenic mouse model
Myotonic dystrophy mouse models
Myostatin
GABA
Acetylcholinesterase knockout mouse
DMSXL mice
Oligodendrocyte
CTG repeats
GSK3
Heart
Cytoskeleton
Endurance training
Transcriptomics
Heart failure
Male
CONGENITAL MYATHENIC SYNDROME
PCR
Central nervous system
RNA interference
CRISPR/Cas9
CTG repeat instability
DMPK
Centronuclear myopathy
Antisense oligonucleotides
Antisense oligonucleotide
Myotonic Dystrophy type 1
Expression