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CMIP is a negative regulator of T cell signaling

Abstract : Upon interaction with cognate antigen, T cells integrate different extra and intracellular signals, involving basal and induced protein-protein interactions as well as binding of proteins to lipids, which can lead to either cell activation or inhibition. Here we show that selective T-cell expression of CMIP, a new adaptor protein, by targeted transgenesis drives
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https://hal.u-pec.fr//hal-03128902
Contributor : Mario Ollero <>
Submitted on : Tuesday, February 2, 2021 - 3:19:46 PM
Last modification on : Thursday, April 15, 2021 - 3:08:11 PM
Long-term archiving on: : Monday, May 3, 2021 - 8:12:41 PM

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Julie Oniszczuk, Kelhia Sendeyo, Cerina Chhuon, Berkan Savas, Etienne Cogné, et al.. CMIP is a negative regulator of T cell signaling. Cellular and molecular immunology, Nature Publishing Group/Chinese Society of Immunology, 2020, 17 (10), pp.1026-1041. ⟨10.1038/s41423-019-0266-5⟩. ⟨hal-03128902⟩

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