CMIP is a negative regulator of T cell signaling
Résumé
Upon interaction with cognate antigen, T cells integrate different extra and intracellular signals, involving basal and induced protein-protein interactions as well as binding of proteins to lipids, which can lead to either cell activation or inhibition. Here we show that selective T-cell expression of CMIP, a new adaptor protein, by targeted transgenesis drives
Domaines
Sciences du Vivant [q-bio]
Origine : Fichiers produits par l'(les) auteur(s)