Evaluation of the Gradient Concentration Strip Method for Antifungal Susceptibility Testing of Isavuconazole and Comparators for Mucorales Species - Université Paris-Est-Créteil-Val-de-Marne Access content directly
Journal Articles Antimicrobial Agents and Chemotherapy Year : 2019

Evaluation of the Gradient Concentration Strip Method for Antifungal Susceptibility Testing of Isavuconazole and Comparators for Mucorales Species

Abstract

MIC values for amphotericin B and three azoles determined by the EUCAST reference technique and by gradient concentration strips were compared for 30 Mucorales isolates belonging to clinically important species. Essential agreement (EA) within ±2 dilution steps at 24 hours between the techniques was 83.3% for isavuconazole. EAs for itraconazole, amphotericin B, and posaconazole were 86.7%, 73.3%, and 56.7%, respectively.

Dates and versions

hal-03997639 , version 1 (20-02-2023)

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Pauline Vidal, Patrick Schwarz, Eric Dannaoui. Evaluation of the Gradient Concentration Strip Method for Antifungal Susceptibility Testing of Isavuconazole and Comparators for Mucorales Species. Antimicrobial Agents and Chemotherapy, 2019, 63 (10), ⟨10.1128/AAC.00838-19⟩. ⟨hal-03997639⟩
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