Should We Quantify Valvular Calcifications on Cardiac CT in Patients with Infective Endocarditis? - Université Paris-Est-Créteil-Val-de-Marne Access content directly
Journal Articles Journal of Clinical Medicine Year : 2021

Should We Quantify Valvular Calcifications on Cardiac CT in Patients with Infective Endocarditis?

Abstract

Background: Evaluate the impact of valvular calcifications measured on cardiac computed tomography (CCT) in patients with infective endocarditis (IE). Methods: Seventy patients with native IE (36 aortic IE, 31 mitral IE, 3 bivalvular IE) were included and explored with CCT between January 2016 and April 2018. Mitral and aortic valvular calcium score (VCS) were measured on unenhanced calcium scoring images, and correlated with clinical, surgical data, and 1-year death rate. Results: VCS of patients with mitral IE and no peripheral embolism was higher than those with peripheral embolism (868 (25-1725) vs. 6 (0-95), p < 0.05). Patients with high calcified mitral IE (mitral VCS > 100; n = 15) had a lower rate of surgery (40.0% vs.78.9%; p = 0.03) and a higher 1-year-death risk (53.3% vs. 10.5%, p = 0.04; OR = 8.5 (2.75-16.40) than patients with low mitral VCS (n = 19). Patients with aortic IE and high aortic calcifications (aortic VCS > 100; n = 18) present more frequently atypical bacteria on blood cultures (33.3% vs. 4.8%; p = 0.03) than patients with low aortic VCS (n = 21). Conclusion: The amount of valvular calcifications on CT was associated with embolism risk, rate of surgery and 1-year risk of death in patients with mitral IE, and germ's type in aortic IE raising the question of their systematic quantification in native IE.
Fichier principal
Vignette du fichier
jcm-10-04458.pdf (1.62 Mo) Télécharger le fichier
Origin : Publisher files allowed on an open archive

Dates and versions

hal-04154451 , version 1 (06-07-2023)

Identifiers

Cite

Virgile Chevance, Remi Valter, Mohamed Refaat Nouri, Islem Sifaoui, Amina Moussafeur, et al.. Should We Quantify Valvular Calcifications on Cardiac CT in Patients with Infective Endocarditis?. Journal of Clinical Medicine, 2021, 10 (19), pp.4458. ⟨10.3390/jcm10194458⟩. ⟨hal-04154451⟩

Collections

INSERM IMRB UPEC
3 View
9 Download

Altmetric

Share

Gmail Facebook X LinkedIn More