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Conference Papers Year : 2022

A multi-scale model for CD8+ T cell immune response

Abstract

CD8+ T cells are important for immune responses against viruses and bacteria, as well as for tumor surveillance. When the CD8+ T cell recognizes its antigen (i.e. it enters in contact with an antigen presenting cell), it gets activated, it then differentiates into an effector, and kills infected or malignant cells bearing the antigen. Meanwhile, part of activated CD8+ T cells differentiate into memory cells. CD8+ T cell activation, differentiation, proliferation and death are controlled by intracellular signaling based on cell interactions with their mi- croenvironment and gene regulation (1), (2). Here we present a multiscale model for CD8+ T cell immune response.
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Dates and versions

hal-04193666 , version 1 (01-09-2023)

Identifiers

  • HAL Id : hal-04193666 , version 1

Cite

Fabien Crauste, Olivier Gandrillon, Madge Martin, Thi Nhu Thao Nguyen, Samuel Bernard. A multi-scale model for CD8+ T cell immune response. Journées Math Bio Santé 2022, GDR MathSAV; GT Mabiome, Oct 2022, Besançon, France. ⟨hal-04193666⟩
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