Is hypoxemia explained by intracardiac or intrapulmonary shunt in COVID-19-related acute respiratory distress syndrome? - Université Paris-Est-Créteil-Val-de-Marne Access content directly
Journal Articles Annals of Intensive Care Year : 2020

Is hypoxemia explained by intracardiac or intrapulmonary shunt in COVID-19-related acute respiratory distress syndrome?

Paul Masi
François Bagate
  • Function : Author
Thomas D’humières
  • Function : Author
Lara Al-Assaad
  • Function : Author
Laure Abou Chakra
  • Function : Author
Armand Mekontso Dessap

Abstract

Abstract Hypoxemia is the main feature of COVID-19-related acute respiratory distress syndrome (C-ARDS), but its underlying mechanisms are debated, especially in patients with low respiratory system elastance (Ers). We assessed 60 critically ill patients hospitalized in our intensive care unit for C-ARDS. We used contrast transthoracic echocardiography to assess patent foramen ovale (PFO) shunt and transpulmonary bubble transit (TPBT). The median Ers was 32 cmH 2 O/L. PFO shunt was detected in six (10%) patients and TPBT in 12 (20%) patients. PFO shunt and TPBT were similar in patients with higher or lower Ers. In conclusion, PFO and TPBT do not seem to be the main drivers of hypoxemia in C-ARDS, especially in patients with lower Ers.

Dates and versions

hal-04394976 , version 1 (15-01-2024)

Identifiers

Cite

Paul Masi, François Bagate, Thomas D’humières, Lara Al-Assaad, Laure Abou Chakra, et al.. Is hypoxemia explained by intracardiac or intrapulmonary shunt in COVID-19-related acute respiratory distress syndrome?. Annals of Intensive Care, 2020, 10 (1), pp.108. ⟨10.1186/s13613-020-00726-z⟩. ⟨hal-04394976⟩

Collections

IMRB UPEC
3 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More