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Journal Articles PACE - Pacing and Clinical Electrophysiology Year : 2020

Implantable cardiac defibrillator leads dysfunction after LVAD implantation

Vincent Galand
Christophe Leclercq
  • Function : Author
Hamed Bourenane
  • Function : Author
Stéphane Boulé
  • Function : Author
André Vincentelli
  • Function : Author
Philippe Maury
  • Function : Author
Pierre Mondoly
  • Function : Author
François Picard
  • Function : Author
Nicolas Welté
  • Function : Author
Michel Kindo
  • Function : Author
Thomas Cardi
  • Function : Author
Jean‐luc Pasquié
  • Function : Author
Philippe Gaudard
  • Function : Author
Jean‐baptiste Gourraud
  • Function : Author
Vincent Probst
  • Function : Author
Pascal Defaye
  • Function : Author
Aude Boignard
  • Function : Author
Marylou Para
  • Function : Author
Vincent Algalarrondo
  • Function : Author
Edeline Pelcé
  • Function : Author
Vlad Gariboldi
  • Function : Author
Matteo Pozzi
  • Function : Author
Jean‐françois Obadia
  • Function : Author
Frédéric Anselme
  • Function : Author
Pierre‐yves Litzler
  • Function : Author
Katrien Blanchart
  • Function : Author
Gerard Babatasi
  • Function : Author
Fabien Garnier
  • Function : Author
Marie Bielefeld
  • Function : Author
David Hamon
  • Function : Author
Thierry Bourguignon
  • Function : Author
Bertrand Pierre
  • Function : Author
Romain Eschalier
  • Function : Author
Nicolas d'Ostrevy
  • Function : Author
  • PersonId : 1345629
  • IdHAL : ndostrevy
Emilie Varlet
  • Function : Author
Eloi Marijon
  • Function : Author
Hugues Blangy
  • Function : Author
Nicolas Sadoul
  • Function : Author
Erwan Flécher
  • Function : Author
Raphaël Martins

Abstract

Abstract Background Implantable cardioverter‐defibrillator (ICD) lead dysfunction has been reported after left ventricular assist device (LVAD) implantation in limited single‐center studies. We aimed at describing and characterizing the incidence of ICD lead parameters dysfunction after LVAD implantation. Methods Among the 652 patients enrolled in the ASSIST‐ICD study, only patients with an ICD prior to LVAD were included (n = 401). ICD lead parameters dysfunction following LVAD implantation is defined as follows: (a) >50% decrease in sensing threshold, (b) pacing lead impedance increase/decrease by >100Ω, and (c) >50% increase in pacing threshold. Results One hundred twenty‐two patients with an ICD prior to LVAD had available ICD interrogation reports prior and after LVAD. A total of 67 (55%) patients exhibited at least one significant lead dysfunction: 17 (15%) exhibited >50% decrease in right ventricular (RV) sensing, 51 (42%) had >100 Ω increase/decrease in RV pacing impedance, and 24 (20%) experienced >50% increase in RV pacing threshold. A total of 52 patients experienced ventricular arrhythmia during follow‐up and all were successfully detected and treated by the device. All lead dysfunction could be managed conservatively. Conclusion More than 50% of LVAD‐recipients may experience >1 significant change in lead parameters but none had severe clinical consequences.

Dates and versions

hal-04395597 , version 1 (15-01-2024)

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Vincent Galand, Christophe Leclercq, Hamed Bourenane, Stéphane Boulé, André Vincentelli, et al.. Implantable cardiac defibrillator leads dysfunction after LVAD implantation. PACE - Pacing and Clinical Electrophysiology, 2020, 43 (11), pp.1309-1317. ⟨10.1111/pace.14004⟩. ⟨hal-04395597⟩

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