In Vitro Antifungal Combination of Flucytosine with Amphotericin B, Voriconazole, or Micafungin against Candida auris Shows No Antagonism - Université Paris-Est-Créteil-Val-de-Marne
Journal Articles Antimicrobial Agents and Chemotherapy Year : 2019

In Vitro Antifungal Combination of Flucytosine with Amphotericin B, Voriconazole, or Micafungin against Candida auris Shows No Antagonism

A. Bidaud
  • Function : Author
F. Botterel
A. Chowdhary

Abstract

Candida auris is an emerging, multidrug-resistant pathogen responsible for invasive hospital-acquired infections. Flucytosine is an effective anti- Candida species drug, but which cannot be used as a monotherapy because of the risk of development of resistant mutants during treatment. It is, therefore, noteworthy to test possible combinations with flucytosine that may have a synergistic interaction.
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Dates and versions

hal-03997625 , version 1 (04-09-2024)

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A. Bidaud, F. Botterel, A. Chowdhary, E. Dannaoui. In Vitro Antifungal Combination of Flucytosine with Amphotericin B, Voriconazole, or Micafungin against Candida auris Shows No Antagonism. Antimicrobial Agents and Chemotherapy, 2019, 63 (12), ⟨10.1128/AAC.01393-19⟩. ⟨hal-03997625⟩
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