In Vitro Antifungal Combination of Flucytosine with Amphotericin B, Voriconazole, or Micafungin against Candida auris Shows No Antagonism
Résumé
Candida auris is an emerging, multidrug-resistant pathogen responsible for invasive hospital-acquired infections. Flucytosine is an effective anti- Candida species drug, but which cannot be used as a monotherapy because of the risk of development of resistant mutants during treatment. It is, therefore, noteworthy to test possible combinations with flucytosine that may have a synergistic interaction.
Domaines
Sciences du Vivant [q-bio]
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bidaud-et-al-2019-in-vitro-antifungal-combination-of-flucytosine-with-amphotericin-b-voriconazole-or-micafungin-against.pdf (815.96 Ko)
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