Prospective evaluation of cardio-metabolic comorbidities in a cohort of patients with non-cystic fibrosis bronchiectasis - Université Paris-Est-Créteil-Val-de-Marne Access content directly
Reports Year : 2021

Prospective evaluation of cardio-metabolic comorbidities in a cohort of patients with non-cystic fibrosis bronchiectasis

Valentine Bonnefoy
  • Function : Author
Etienne Audureau
  • Function : Author
Laurence Bassinet
  • Function : Author
Sonia Zebachi
  • Function : Author
Benoit Douvry
  • Function : Author
Isabelle Monnet
  • Function : Author
Gilles Mangiapan
  • Function : Author
Amel Boudjemaa
  • Function : Author
Caroline Touboul
  • Function : Author
Laura Ernande
  • Function : Author
Bruno Housset
  • Function : Author
Bernard Maitre
  • Function : Author
Frederic Schlemmer
  • Function : Author

Abstract

Results In total, 336 of 457 patients with MINOCA underwent CMR. CMR was able to identify a diagnosis in 90.5% of cases, and changed the underlying cause in 35.7% of patients; 33.7% of type 1 MI were not diagnosed prior to CMR. Patients with a normal CMR had a significantly longer median time to complete the CMR (17 vs. 7 days, P = 4.2E-7) and lower conventional and high sensitivity troponin values (respectively 1.1 vs. 3.6 G/L, P = 0.002 and 433.3 vs. 707.1 ng/L, P = 0.007). At 1-year follow-up of the CMR cohort, the prevalence of all-cause mortality was 3%, of cardiac mortality 0.6% and of rehospitalisation for cardiac causes 7.8%. No bleeding disorders occurred after increased anti-platelet therapy in patients re-diagnosed with MI (Fig. 1). Conclusion CMR provided a diagnosis in 9 out of 10 patients presenting with MINOCA. The diagnosis differed from the one prior to CMR in 35.7% of patients. The systematic use of CMR plays a pivotal role in identifying the underlying cause of myocardial injury, impacting both individuals, health professionals and society at large.
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Dates and versions

hal-04394869 , version 1 (15-01-2024)

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Valentine Bonnefoy, Laurent Boyer, Etienne Audureau, Laurence Bassinet, Sonia Zebachi, et al.. Prospective evaluation of cardio-metabolic comorbidities in a cohort of patients with non-cystic fibrosis bronchiectasis. IMRB. 2021, pp.2724. ⟨hal-04394869⟩

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