Antibacterial and antioxidant photoinitiated epoxy co-networks of resorcinol and eugenol derivatives
Abstract
In this study, we used photo-induced cationic reactions to design bio-based crosslinked co-networks from resorcinol diglycidyl ether (R) and an eugenol derivative (epoxy eugenol EE) synthesized by nucleophilic substitution. The aim of this work is to prepare new UV-cured co-networks thanks to the cationic polymerization of the epoxides with a covalent immobilization of the eugenol derivative (EE) as antioxidant and antibacterial agent to investigate the impact of the proportion of this one on biological activities. Moreover, the antibacterial and antioxidant properties of the networks were studied in vitro against two pathogenic bacteria strains: Escherichia coli and Staphylococcus aureus and the DPPH method respectively. The results had shownon the one hand a promising anti-adherence forthe both strains without any diffusion of the eugenol derivative which will allow potential applications of these networks for anti-bacterial adhesion and, on the other hand an anti-oxidant activity.