Electrospun Nanofibrous Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) With Antibacterial Activity - Université Paris-Est-Créteil-Val-de-Marne Access content directly
Journal Articles Journal of Biology Engineering and Medicine Year : 2019

Electrospun Nanofibrous Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) With Antibacterial Activity

Davy Louis Versace
  • Function : Author
Estelle Renard
  • Function : Author
Etienne Dessauw
  • Function : Author
Valerie Langlois
  • Function : Author

Abstract

Elaboration of electrospun nanofibrous poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBHV)-based mats was implemented through two routes to obtain antibacterial material containing carvacrol, a phenolic compound extracted from essential oils. The first strategy relied on a direct blend of PHBHV and carvacrol/-cyclodextrin inclusion complexes, PHBHV (carvCD-IC), while the second approach implied the elaboration of multilayered scaffold via the introduction of poly(β-CD-epichlorohydrin), PolyCD. The PolyCD/carv-based mat was electrospun between two hydrophobic PHBHV mats. Scanning Electron Microscopy analysis of mats showed uniform and beadless fibers. The three layered materials [PHBHV-(PolyCD/carv)-PHBHV] is sufficient to ensure optimal antiradical activity (RSA of 88.6%) and exhibit interesting antibacterial activities against E. coli and S. aureus.

Dates and versions

hal-04473750 , version 1 (22-02-2024)

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Cite

Samir Abbad Andaloussi, Davy Louis Versace, Estelle Renard, Etienne Dessauw, Valerie Langlois. Electrospun Nanofibrous Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) With Antibacterial Activity. Journal of Biology Engineering and Medicine, 2019, pp.1-7. ⟨10.31487/j.JBEM.2019.01.02⟩. ⟨hal-04473750⟩
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